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A control group receives no treatment and no fake procedure, so the effect being studied is simply withheld. Which control is this?

Answer: Negative Control

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A p-value is 0.02 when the cutoff for significance is 0.05. How should the result be interpreted?

Answer: Statistically significant

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A treatment increases Protein A from 0.1 M to 0.5 M and Protein B from 0.001 M to 0.2 M. Which protein had the greater potentiation factor?

Answer: Protein B

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A control group receives a sugar pill to control for psychological effects of a painkiller study. Which control is this?

Answer: Placebo Control

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A variable changes the strength or direction of the relationship between the independent and dependent variables. Which variable type is this?

Answer: Moderating variable

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A study concludes that a cancer drug does not work, but in reality the drug truly does treat the cancer. Which error occurred?

Answer: Type II error

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A cell displays internal viral or cancerous proteins to CD8 positive cytotoxic T cells. Which MHC class does this?

Answer: MHC Class I

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An antigen-presenting cell displays an external bacterial, fungal, or parasitic antigen to CD4 positive helper T cells. Which MHC class does this?

Answer: MHC Class II

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The part of an antibody that binds the antigen varies between antibodies. Which region is this?

Answer: Variable Region

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A membrane protein uses calcium to bind to the same type of protein on another cell, creating tight cell-to-cell junctions. Which adhesion protein is this?

Answer: Cadherin

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The part of the antibody variable region specifically binds the epitope on the pathogen. Which term describes this antibody part?

Answer: Paratope

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A cellular protein binds carbohydrates on other cells, commonly for cell communication in immune contexts. Which adhesion protein is this?

Answer: Selectin

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A hormone from adipose tissue signals fullness when fat stores are growing or food is in the gut. Which hormone is this?

Answer: Leptin

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A kidney hormone starts the RAAS pathway to eventually raise blood pressure through aldosterone. Which hormone is this?

Answer: Renin

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A hormone supports T cell development and differentiation and is more important in development than adulthood. Which hormone is this?

Answer: Thymosin

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A kidney hormone increases red blood cell synthesis in bone marrow in response to low oxygen. Which hormone is this?

Answer: Erythropoietin

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A kidney hormone is the active form of Vitamin D and helps PTH raise blood calcium. Which hormone is this?

Answer: Calcitriol

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A hormone is released by the heart in response to atrial stretch from high blood pressure. Which hormone is this?

Answer: ANP

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A hormone is mainly produced by the stomach and signals that the body needs to eat more. Which hormone is this?

Answer: Ghrelin

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A hormone is produced by delta islet cells and inhibits many processes, acting like a global pause button. Which hormone is this?

Answer: Somatostatin

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A hormone stimulates bile release from the gallbladder and helps stimulate digestive enzyme release. Which hormone is this?

Answer: CCK

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A hormone is released by alpha islet cells and promotes gluconeogenesis, glycogenolysis, and fatty acid oxidation. Which hormone is this?

Answer: Glucagon

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A hormone slows digestive motility and causes bicarbonate release to reduce acidity in the duodenum. Which hormone is this?

Answer: Secretin

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A hormone is secreted by G cells and stimulates parietal cells to release HCl. Which hormone is this?

Answer: Gastrin

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A fetal shunt connects the pulmonary artery to the aorta. Which shunt is this?

Answer: Ductus arteriosus

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A fetal shunt connects the umbilical vein with the inferior vena cava. Which shunt is this?

Answer: Ductus venosus

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A molecule is released into a duct or open area to travel to a distant place, but not through blood. Which secretion type is this?

Answer: Exocrine

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A signal is released to a cell directly next to the releasing cell. Which type of communication is this?

Answer: Juxtacrine

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A signal is released to nearby cells in the same general area, but not into the bloodstream. Which type is this?

Answer: Paracrine

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A fetal hemoglobin curve is left-shifted compared with maternal hemoglobin. What does this mean?

Answer: Fetal hemoglobin has higher oxygen affinity

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During PCR, primers bind to target sequences after cooling. Which step is this?

Answer: Annealing

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A restriction enzyme is most likely to recognize which type of DNA sequence?

Answer: Palindromic sequence

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During PCR, heat splits hydrogen bonds between DNA strands. Which step is this?

Answer: Denaturation

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A technique amplifies DNA using denaturation, annealing, and extension. Which technique is being described?

Answer: PCR

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A researcher wants to measure the exact concentration of a gene using fluorescence during PCR. Which technique is best?

Answer: qPCR

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A sequence is 5’-GAATTC-3’, and its complement reads the same in the 5’ to 3’ direction after being flipped. Which term describes this?

Answer: Palindrome

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A protein provides waterproofing in epidermal tissue. Which structural protein is this?

Answer: Keratin

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A binding protein in blood carries four oxygen molecules and shows cooperativity. Which protein is this?

Answer: Hemoglobin

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A motor protein carries cellular components away from the nucleus in the positive or anterograde direction. Which protein is this?

Answer: Kinesin

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A protein in blood binds nonpolar molecules such as fatty acids, steroid hormones, bilirubin, and some drugs. Which protein is this?

Answer: Albumin

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A cytoskeleton protein forms microtubules and serves as a highway for cellular transport. Which protein is this?

Answer: Tubulin

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A muscle oxygen storage protein binds only one oxygen and is not cooperative. Which protein is this?

Answer: Myoglobin

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A sperm region has many mitochondria and generates ATP from fructose in semen. Which region is this?

Answer: Midpiece

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The sperm uses a modified Golgi body to penetrate the ovum. Which structure is this?

Answer: Acrosome

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A GPCR target protein produces cAMP after being activated. Which enzyme commonly makes cAMP in this pathway?

Answer: Adenylate cyclase

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A protein on the surface of sperm binds zona pellucida receptors of the ova. Which protein is this?

Answer: Bindin

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A ligand binds a GPCR, causing G alpha to exchange GDP for GTP. What happens next?

Answer: G alpha-GTP dissociates from beta and gamma

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A receptor dimer has an exterior ligand binding domain and interior enzymatic domains that phosphorylate tyrosines. Which receptor is this?

Answer: RTK

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A hormone stimulates uterine contractions during childbirth and milk letdown, but not milk production. Which hormone is this?

Answer: Oxytocin

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A hormone from the adrenal cortex increases salt reabsorption in the distal convoluted tubule, raising blood pressure and volume without changing osmolarity. Which hormone is this?

Answer: Aldosterone

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A hormone from sustentacular cells inhibits FSH and LH. Which hormone is this?

Answer: Inhibin

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A hormone causes mammary glands to produce milk. Which hormone is this?

Answer: Prolactin

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Dopamine from the hypothalamus prevents milk production by inhibiting which hormone?

Answer: Prolactin

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A hormone from the adrenal cortex raises glucose levels by stimulating gluconeogenesis and decreasing protein synthesis. Which hormone is this?

Answer: Cortisol

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A female somatic cell randomly inactivates one X chromosome. What is the inactive X chromosome called?

Answer: Barr body

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A pregnancy implants in the fallopian tube instead of the uterus, potentially because cilia failed to move the fertilized egg properly. Which condition is this?

Answer: Ectopic pregnancy

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If fertilization does not occur, the corpus luteum is no longer needed and becomes which structure?

Answer: Corpus albicans

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A hormone maintains the corpus luteum after fertilization so estrogen and progesterone do not drop early in pregnancy. Which hormone is this?

Answer: hCG

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Two separate eggs are fertilized by two separate sperm, producing siblings with similar but non-identical genomes. Which type of twins are these?

Answer: Fraternal twins

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One zygote splits into two embryos with identical genomes. Which type of twins are produced?

Answer: Identical twins

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A population selects against both extreme phenotypes, making the intermediate heterozygotes more common. Which selection type is this?

Answer: Stabilizing selection

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One extreme phenotype is selected against, making the other extreme more common. Which selection type is this?

Answer: Directional selection

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Recently diverged species adapt similar traits over time due to similar environmental pressures. Which pattern is this?

Answer: Parallel evolution

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Recently diverged species become more different over time. Which evolutionary pattern is this?

Answer: Divergent evolution

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Distantly related species adapt similar traits over time because they live in similar environments. Which evolutionary pattern is this?

Answer: Convergent evolution

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Intermediate heterozygotes are selected against, favoring both extremes. Which selection type is this?

Answer: Disruptive selection

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In a monohybrid cross Dd x dd, what fraction of offspring display the dominant phenotype?

Answer: 1/2

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In Hardy-Weinberg, 2pq represents which genotype frequency?

Answer: Heterozygous

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Alleles that are closer together on a chromosome are separated less often during crossing over. Which term is lower for these alleles?

Answer: Recombination frequency

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In a monohybrid cross Dd x Dd, what fraction of offspring are expected to be homozygous recessive?

Answer: 1/4

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In an Aa x Aa cross where aa is lethal, what fraction of surviving offspring are expected to be Aa?

Answer: 2/3

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In Hardy-Weinberg, q² represents which genotype frequency?

Answer: Homozygous recessive

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Two variables change together mathematically, but one is not shown to directly cause the other. Which conclusion is supported?

Answer: Correlation

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Both participants and observers do not know who received the placebo or the experimental drug. Which study design is this?

Answer: Double Blind

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A study result is truly caused by the independent variable rather than confounding variables. Which validity is high?

Answer: Internal Validity

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Error bars for two groups overlap. What should be concluded from the document’s rule?

Answer: The groups should be treated as the same

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Only participants are unaware of whether they received the placebo or treatment, but observers know. Which design is this?

Answer: Single Blind

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A study can be generalized only poorly because it tests a drug only on 25-year-old males but claims results for all humans. Which validity is low?

Answer: External Validity

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SDS is added to proteins, giving them a uniformly negative charge and disrupting noncovalent quaternary interactions, but disulfide bonds remain intact. Which technique is this?

Answer: Nonreducing SDS PAGE

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A blot detects whether a specific protein of known weight is present after reducing SDS PAGE. Which technique is this?

Answer: Western Blotting

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A DNA gel shows a thicker band for one sample than another at the same location. What does the thicker band mean?

Answer: Higher concentration of that DNA

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SDS and a reducing agent are added, causing all protein subunits to separate, including those held by disulfide bonds. Which technique is this?

Answer: Reducing SDS PAGE

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PCR starts with 3 copies of DNA and runs for 4 rounds. How many copies are produced?

Answer: 48

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A gel technique preserves a protein’s natural size, shape, and charge because nothing is added before running the gel. Which technique is this?

Answer: Native PAGE

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A sarcomere region contains only thick filaments and gets smaller during contraction. Which region is this?

Answer: H zone

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A sarcomere band spans the entire thick filament and does not change size during contraction. Which band is this?

Answer: A band

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A muscle fiber is pale, has fewer mitochondria, relies mainly on anaerobic metabolism, and is best for short bursts. Which fiber type is this?

Answer: Fast/White Fiber

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A muscle cell has many nuclei and behaves as one cell with many copies of the same organelle. Which term describes this?

Answer: Structural Syncytium

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Many individual cardiac muscle cells work together as if they were one cell because they are connected by gap junctions. Which term describes this?

Answer: Functional Syncytium

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A muscle fiber appears red because it has many mitochondria and uses oxidative phosphorylation for long-term contractions. Which fiber type is this?

Answer: Slow/Red Fiber

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A neuron increases the intensity of its signal. According to the document, what must increase?

Answer: Frequency of action potentials

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Voltage gated Na channels open and Na rushes into the cell, making the inside much more positive. Which phase is this?

Answer: Depolarization

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A neuron reaches about -50 to -55 mV, causing voltage gated sodium channels to open and the cell to immediately depolarize. Which voltage is this?

Answer: Threshold Voltage

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The membrane potential goes past resting membrane potential to become more negative than normal because K channels are slow to close. Which phase is this?

Answer: Hyperpolarization

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The inside of a neuron is at about -70 mV due to K leak channels and the NaK ATPase. Which state is this?

Answer: Resting Membrane Potential

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Voltage gated K channels open after the inside of the cell becomes very positive, allowing K to leave and the membrane potential to move back toward RMP. Which phase is this?

Answer: Repolarization

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A cell commits to becoming nervous tissue, but the physical changes have not occurred yet. Which process is this?

Answer: Determination

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A tissue can regrow an identical copy of itself after damage, like the liver. Which term describes this?

Answer: Regenerative Capacity

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A cell physically changes shape and function after being committed to a lineage. Which process is this?

Answer: Differentiation

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A signal acts on the same cell that released it. Which communication type is this?

Answer: Autocrine

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